| Pharmacy Drug Brand Name: | Faslodex® |
| Active Ingredient(s): | fulvestrant |
| Strength(s) / Dose(s): | 50 mg/ml (available in one 250 mg or two 125 mg pre-filled syringes) |
| Delivery / Dosage Form(s): | Intramuscular Injection |
| Company Manufacturer Name: | AstraZeneca Pharmaceuticals LP |
| Availability / Prescription: | Prescription only |
| FDA Approval Date *: | April 25, 2002 |
* Approval by the FDA does not necessarily mean that this drug is available for consumers at this time.
What is Faslodex used for?
FASLODEX is used to treat hormone receptor positive breast cancer in postmenopausal women whose disease or damage has spread after treatment with antiestrogens, primarily tamoxifen. Postmenopausal women are women who have gone through the "change of life", and are no longer having menstrual cycles.
How does Faslodex work?
Many breast cancer tumors have hormone receptors, which are stimulated by estrogen and cause the tumors to grow. Faslodex and Tamoxifen are antiestrogens, which may block the action of estrogen on cancer cells, and may cause some breast cancer tumors to shrink.
Who should not use Faslodex?
Do not use Faslodex if you:
- have not been treated with Tamoxifen or another antiestrogen medicine first
- are pregnant. Faslodex may cause birth defects or miscarriage
- are allergic to Faslodex or to any of the ingredients in Faslodex
What should I tell my health care (healthcare) provider?
Tell your health care (healthcare) provider if you:
- are still having menstrual periods
- are pregnant, are planning to become pregnant or are breast-feeding
- have or had liver problems
- bleed easily
- are taking anticoagulants (blood thinners)
- have a low level of platelets in your blood
Tell your health care (healthcare) provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Faslodex works or Faslodex may affect how your other medicines work.
What are some possible side effects of Faslodex? (This is not a comprehensive list of possible side effects reported with Faslodex. Your doctor or pharmacist can provide expert advice on the possible side effects of this drug.)
Side effects of Faslodex include:
- nausea
- weakness
- pain or discomfort
- hot flashes
- sore throat
- bone pain or discomfort
- headache
- shortness of breath
- back pain or discomfort
- vomiting
- constipation
- diarrhea
- stomach pain or discomfort
- pain or discomfort, redness and swelling at the injection site
- cough
- pelvic pain or discomfort
- loss of appetite
- swelling of the extremities (arms and legs)
- rash
- chest pain or discomfort
- flu symptoms
- dizziness
- trouble sleeping
- fever
- increased skin sensations (including numbness, tingling, burning, prickling)
- urinary tract infection
- depression
- anxiety
- sweating