Aloxi Prescription Drug Pharmaceutical Information

• right away with certain anti-cancer medicines (chemotherapy).
• later after taking certain anti-cancer medicines

Aloxi is not used to treat the nausea and vomiting you may already have. Aloxi has not been studied in children under 18 years of age.

Who should not take Aloxi?

Do not take Aloxi if you are allergic to Aloxi or any of its ingredients.

General Precautions with Aloxi:

• If you are allergic to other medicines like Aloxi, such as ondansetron (Zofran®), dolasetron (Anzemet®), or granisetron (Kytril®), you are more likely to have an allergic reaction with Aloxi.
• Aloxi may affect your heartbeat. This may cause serious problems, especially in people who:
  • already have heartbeat problems or irregular heartbeat (especially a condition called QT prolongation)
  • are taking medicine to control a heartbeat problem
  • are taking medicines called diuretics ("water pills")
  • have low levels of potassium and magnesium in their blood

What should I tell my health care (healthcare) provider?

Tell your health care (healthcare) provider:

• if you are pregnant or planning to become pregnant.
• if you are breast-feeding.

Tell your health care (healthcare) provider about ALL the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Aloxi works or Aloxi may affect how your other medicines work.

What are some possible side effects of Aloxi? (This is not a comprehensive list of possible side effects assosciated with Aloxi. Your doctor or pharmacist can provide expert advice on the possible side effects of this drug.)

Some common side effects with Aloxi include:

• headache
• constipation
• diarrhea
• dizziness
• tiredness
• stomach area pain or discomfort
• trouble sleeping